Septins Regulate Border Cell Shape and Surface Geometry ownstream of Rho

Gabbert, A., Mondo, J., Campanale, J., Mitchell, N., Myers, A., Streichan, S., Miolane, N., Montell, D.

Septins self-assemble into polymers that bind and deform membranes in vitro and regulate diverse cell behaviors in vivo. How their in vitro properties relate to their in vivo functions is under active investigation. Here we uncover requirements for septins in detachment and motility of border cell clusters in the Drosophila ovary.